Recent Molecular Biology News
Generating bispecific human IgG1 and IgG2 antibodies from any antibody pair.
Posted from Journal of Molecular Biology 20 days ago
Molecular Biology : Molecular Biology Journals
Publication Date: 2012 Apr 25 PMID: 22543237Authors: Strop, P. - Ho, W. H. - Boustany, L. M. - Abdiche, Y. N. - Lindquist, K. C. - Farias, S. E. - Rickert, M. - Appah, C. T. - Pascua, E. - Radcliffe, T. - Sutton, J. - Chaparro-Riggers, J. - Chen, W. - Casas, M. G. - Chin, M. S. - Wong, O. K. - Liu, ... (original story)
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Nucleobindin 1 Caps Human Islet Amyloid Polypeptide Protofibrils to Prevent Amyloid Fibril Formation.
Posted from Journal of Molecular Biology 20 days ago
Molecular Biology : Molecular Biology Journals
Publication Date: 2012 Apr 24 PMID: 22542527Authors: Gupta, R. - Kapoor, N. - Raleigh, D. P. - Sakmar, T. P.Journal: J Mol BiolMany human diseases are associated with amyloid fibril deposition, including type 2 diabetes mellitus where human islet amyloid polypeptide (hIAPP) forms fibrils in the panc... (original story)
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Plasmodium falciparum SSB Tetramer Wraps Single Stranded DNA with Similar Topology but Opposite Polarity to E. coli SSB.
Posted from Journal of Molecular Biology 20 days ago
Molecular Biology : Molecular Biology Journals
Publication Date: 2012 Apr 26 PMID: 22543099Authors: Antony, E. - Weiland, E. A. - Korolev, S. - Lohman, T. M.Journal: J Mol BiolSingle stranded DNA binding (SSB) proteins play central roles in genome maintenance in all organisms. Plasmodium falciparum, the causative agent of malaria, encodes an SSB... (original story)
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Transient structure and SH3 interaction sites in an intrinsically disordered fragment of the hepatitis C virus protein NS5A.
Posted from Journal of Molecular Biology 20 days ago
Molecular Biology : Molecular Biology Journals
Publication Date: 2012 Apr 25 PMID: 22543239Authors: Feuerstein, S. - Solyom, Z. - Aladag, A. - Favier, A. - Schwarten, M. - Hoffmann, S. - Willbold, D. - Brutscher, B.Journal: J Mol BiolUnderstanding the molecular mechanisms involved in virus replication and particle assembly is of primary fundamen... (original story)
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Combination of the Human Prolyl Isomerase FKBP12 with Unrelated Chaperone Domains Leads to Chimeric Folding Enzymes with High Activity.
Posted from Journal of Molecular Biology 20 days ago
Molecular Biology : Molecular Biology Journals
Publication Date: 2012 Apr 24 PMID: 22542528Authors: Geitner, A. J. - Schmid, F. X.Journal: J Mol BiolFolding enzymes often use distinct domains for the binding of substrate proteins ("chaperone domains") and for the catalysis of slow folding reactions such as disulfide formation or prolyl isomeriza... (original story)
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Early Steps in Oxidation-Induced SOD1 Misfolding: Implications for Non-Amyloid Protein Aggregation in Familial ALS.
Posted from Journal of Molecular Biology 20 days ago
Molecular Biology : Molecular Biology Journals
Publication Date: 2012 Apr 24 PMID: 22542526Authors: Mulligan, V. K. - Kerman, A. - Laister, R. C. - Sharda, P. R. - Arslan, P. E. - Chakrabartty, A.Journal: J Mol BiolAmong the diseases of protein misfolding, amyotrophic lateral sclerosis (ALS) is unusual in that the proteinaceous neuronal inclusio... (original story)
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The Structure of Subunit E of the Pyrococcus horikoshii OT3 A-ATP Synthase Gives Insight into the Elasticity of the Peripheral Stalk.
Posted from Journal of Molecular Biology 29 days ago
Molecular Biology : Molecular Biology Journals
Publication Date: 2012 Apr 16 PMID: 22516614Authors: Balakrishna, A. M. - Hunke, C. - Gruber, G.Journal: J Mol BiolA(1)A(O) ATP synthases are the major energy converters of archaea. They are composed of an A(1) region that synthesizes ATP and an integral part A(O) that conducts ions. Subunit E is a ... (original story)
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Dda Helicase Tightly Couples Translocation on Single-Stranded DNA to Unwinding of Duplex DNA: Dda Is an Optimally Active Helicase.
Posted from Journal of Molecular Biology 29 days ago
Molecular Biology : Molecular Biology Journals
Publication Date: 2012 Apr 11 PMID: 22504228Authors: Byrd, A. K. - Matlock, D. L. - Bagchi, D. - Aarattuthodiyil, S. - Harrison, D. - Croquette, V. - Raney, K. D.Journal: J Mol BiolHelicases utilize the energy of ATP hydrolysis to unwind double-stranded DNA while translocating on the DNA. Mechanisms... (original story)
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Extended local similarity analysis (eLSA) of microbial community and other time series data with replicates
Posted from Josephine Bay Paul Center i... 29 days ago
Molecular Biology : Molecular Biology Information
Extended local similarity analysis (eLSA) of microbial community and other time series data with replicates Xia, Li C.; Steele, Joshua A.; Cram, Jacob A.; Cardon, Zoe G.; Simmons, Sheri L.; Vallino, Joseph J.; Fuhrman, Jed A.; Sun, Fengzhu The increasing availability of time series microbial communi... (original story)
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Structural Comparison of Mouse and Human alpha-Synuclein Amyloid Fibrils by Solid-State NMR.
Posted from Journal of Molecular Biology 29 days ago
Molecular Biology : Molecular Biology Journals
Publication Date: 2012 Apr 16 PMID: 22516611Authors: Lv, G. - Kumar, A. - Giller, K. - Orcellet, M. L. - Riedel, D. - Fernandez, C. O. - Becker, S. - Lange, A.Journal: J Mol BiolFibrillar alpha-synuclein (AS) is the major component of Lewy bodies, the pathological hallmark of Parkinson's disease. Mo... (original story)
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