Recent Molecular Biology Information
QTL Mapping Using a Memetic Algorithm with Modifications of BIC as Fitness Function
Posted from Statistical Applications in... 3 days ago
Molecular Biology : Molecular Biology Information
The problem of locating quantitative trait loci (QTL) for experimental populations can be approached by multiple regression analysis. In this context variable selection using a modification of the Bayesian Information Criterion (mBIC) has been well established in the past. In this article a memet... (original story)
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Exploring Multicollinearity Using a Random Matrix Theory Approach
Posted from Statistical Applications in... 3 days ago
Molecular Biology : Molecular Biology Information
Clustering of gene expression data is often done with the latent aim of dimension reduction, by finding groups of genes that have a common response to potentially unknown stimuli. However, what is poorly understood to date is the behaviour of a low dimensional signal embedded in high dimensions. Thi... (original story)
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Computing Posterior Probabilities for Score-based Alignments Using ppALIGN
Posted from Statistical Applications in... 3 days ago
Molecular Biology : Molecular Biology Information
Score-based pairwise alignments are widely used in bioinformatics in particular with molecular database search tools, such as the BLAST family. Due to sophisticated heuristics, such algorithms are usually fast but the underlying scoring model unfortunately lacks a s... (original story)
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A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency
Posted from Cell Death and Differentiat... 12 days ago
Molecular Biology : Molecular Biology Information
A series of Fas receptor agonist antibodies that demonstrate an inverse correlation between affinity and potency Cell Death and Differentiation advance online publication, January 20, 2012. doi:10.1038/cdd.2011.208 Authors: M Chodorge, S Züger, C Stirnimann, C Briand, L Jermutus, M G... (original story)
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Post-natal cardiomyocytes can generate iPS cells with an enhanced capacity toward cardiomyogenic re-differentation
Posted from Cell Death and Differentiat... 12 days ago
Molecular Biology : Molecular Biology Information
Post-natal cardiomyocytes can generate iPS cells with an enhanced capacity toward cardiomyogenic re-differentation Cell Death and Differentiation advance online publication, January 20, 2012. doi:10.1038/cdd.2011.205 Authors: R Rizzi, E Di Pasquale, P Portararo, R Papait, P Cattaneo, M V ... (original story)
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PED/PEA-15 induces autophagy and mediates TGF-beta1 effect on muscle cell differentiation
Posted from Cell Death and Differentiat... 12 days ago
Molecular Biology : Molecular Biology Information
PED/PEA-15 induces autophagy and mediates TGF-beta1 effect on muscle cell differentiation Cell Death and Differentiation advance online publication, January 27, 2012. doi:10.1038/cdd.2011.201 Authors: S Iovino, F Oriente, G Botta, S Cabaro, V Iovane, O Paciello, D Viggiano, G Perruolo... (original story)
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The Beta-Binomial SGoF method for multiple dependent tests
Posted from Statistical Applications in... 12 days ago
Molecular Biology : Molecular Biology Information
In this paper a correction of SGoF multitesting method for dependent tests is introduced. The correction is based in the beta-binomial model, and therefore the new method is called Beta-Binomial SGoF (or BB-SGoF). Main properties of the new method are established, and its practical implementation is... (original story)
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Borrowing Information Across Genes and Experiments for Improved Error Variance Estimation in Microarray Data Analysis
Posted from Statistical Applications in... 12 days ago
Molecular Biology : Molecular Biology Information
Statistical inference for microarray experiments usually involves the estimation of error variance for each gene. Because the sample size available for each gene is often low, the usual unbiased estimator of the error variance can be unreliable. Shrinkage methods, including empirical Bayes approache... (original story)
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The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo
Posted from Cell Death and Differentiat... 12 days ago
Molecular Biology : Molecular Biology Information
The mitochondrial transporter ABC-me (ABCB10), a downstream target of GATA-1, is essential for erythropoiesis in vivo Cell Death and Differentiation advance online publication, January 13, 2012. doi:10.1038/cdd.2011.195 Authors: B B Hyde, M Liesa, A A Elorza, W Qiu, S E Haigh, L Richey, H... (original story)
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Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1
Posted from Cell Death and Differentiat... 12 days ago
Molecular Biology : Molecular Biology Information
Retinoblastoma tumor-suppressor protein phosphorylation and inactivation depend on direct interaction with Pin1 Cell Death and Differentiation advance online publication, February 10, 2012. doi:10.1038/cdd.2011.202 Authors: F Rizzolio, C Lucchetti, I Caligiuri, I Marchesi, M Caputo, A J K... (original story)
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